Abstract: The technological advances and accumulation of biomedical datasets are yielding unprecedented opportunities to better understand genetic diseases, but necessitate proper exploration and integration methods to unravel a complete picture of biological systems. I will discuss about the computational strategies we recently developed, using i) multilayer networks to integrate a large range of interactions, and associated exploration algorithms and ii) dimensionality reduction to extract biological knowledge simultaneously from multiple omics. On the application side, I will discuss about the analysis of rare genetic diseases, which raise various challenges: many patients are undiagnosed, phenotypes can be highly heterogeneous, and only a few treatments exist.

Place: Virtual seminar via Zoom, with required registration.

Bioinfo4Women seminars / BSC Life Session

Venue: Online seminar - Zoom

Date: 21/01/2021

Time: 12:00

Host: Barcelona Supercomputing Center

Multi-omics data integration methods to study rare genetic diseases


Anaïs Baudot

Creator of the “Networks and Systems Biology for Diseases” team in the Marseille Medica Genetic Unit in 2018.

Pin It on Pinterest