Abstract: The Life Sciences department of the Barcelona Supercomputing Center created the Bioinfo4Women (B4W) programme in 2018 with the aim to enhance gender awareness, in particular in the areas of Personalised Medicine, Bioinformatics and High Performance Computing. For this, B4W is building an international network of outstanding women researchers with training and mentoring plans, study visits at our center and webinars, and thereby multiplying their impact in the society. In addition, the programme is involved in different research projects related to biomedicine with a focus on sex and gender issues, in particular sex and gender differences and biases in biomedical data and Artificial Intelligence (AI). We will present some of the most recent research achievements of the BSC Life Sciences department and B4W in this area, including our work on (1) sex differences in comorbidities and drug administration from electronic health records; (2) the state of sex and gender bias in AI technologies; (3) sex bias assessment in worldwide large repositories of human data; (4) the qualitative analysis of gender bias in AI in the LGBTIQ+ communities.