Abstract: Global heating, extreme climatic events, environmental degradation, and socio-economic inequalities exacerbate the risk of infectious disease emergence, spread and transmission. Mosquito-borne diseases, such as dengue and malaria, are highly sensitive to climate variability and climate change. A warming climate can lengthen the transmission season and alter the geographical range, potentially bringing diseases to regions which lack either population immunity or strong public health infrastructure. More frequent extreme weather events, such as storms, floods, and droughts, also affect the timing and intensity of outbreaks. Mosquitoes thrive in warm and humid conditions with rainfall increasing the number of outdoor breeding sites. However, drought conditions can also promote breeding, due to an increase in water storage containers around the home. Despite the health threats of rapid environmental change, we lack the evidence-base to understand and predict the impacts of extreme events and landscape changes on disease risk, leaving communities vulnerable to increasing health threats. This talk will focus on the present and future risks of mosquito-borne diseases and touch on the partnerships I have built over years with a wide range of scientists and practitioners to link climate science via impact-based forecasting to disease risk management. I will showcase climate-integrated decision support frameworks, which have been co-created with stakeholders in the Americas and Southeast Asia, to improve preparedness and response to emerging infectious disease threats and assist public health services adapt to climate change.